Age-Related Deficits in Spatial Memory and Hippocampal Spines in Virgin, Female Fischer 344 Rats

Effects of aging on memory and brain morphology were examined in aged, 21-month-old, and young, 4-month-old, Fischer 344 female rats. Spatial memory was assessed using the object placement task, and dendritic spine density was determined on pyramidal neurons in the hippocampus following Golgi impreg...

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Bibliographic Details
Main Authors: Victoria N. Luine, Maureen E. Wallace, Maya Frankfurt
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Current Gerontology and Geriatrics Research
Online Access:http://dx.doi.org/10.1155/2011/316386