The logic of EGFR/ErbB signaling: theoretical properties and analysis of high-throughput data.

The epidermal growth factor receptor (EGFR) signaling pathway is probably the best-studied receptor system in mammalian cells, and it also has become a popular example for employing mathematical modeling to cellular signaling networks. Dynamic models have the highest explanatory and predictive poten...

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Bibliographic Details
Main Authors: Regina Samaga, Julio Saez-Rodriguez, Leonidas G Alexopoulos, Peter K Sorger, Steffen Klamt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19662154/?tool=EBI