Engineering Photoactivatability in Genetically Encoded Voltage and pH Indicators

Genetically-encoded indicators of neuronal activity enable the labeling of a genetically defined population of neurons to optically monitor their activities. However, researchers often find difficulties in identifying relevant signals from excessive background fluorescence. A photoactivatable versio...

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Bibliographic Details
Main Authors: Sungmoo Lee, Yoon-Kyu Song, Bradley J. Baker
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00482/full