Challenges and disparities in the application of personalized genomic medicine to populations with African ancestry

Challenges and disparities in the application of personalized genomic medicine to populations with African ancestry

Personalized medicine requires accurate and ethnicity-optimized reference genome panels. Here, the Consortium on Asthma among African-ancestry Populations in the Americas (CAAPA) evaluates typical variant filters and existing genome databases against newly sequenced African-ancestry populations.

Bibliographic Details
Main Authors: Michael D. Kessler, Laura Yerges-Armstrong, Margaret A. Taub, Amol C. Shetty, Kristin Maloney, Linda Jo Bone Jeng, Ingo Ruczinski, Albert M. Levin, L. Keoki Williams, Terri H. Beaty, Rasika A. Mathias, Kathleen C. Barnes, Consortium on Asthma among African-ancestry Populations in the Americas (CAAPA), Timothy D. O’Connor
Format: Article
Language:English
Published: Nature Publishing Group 2016-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12521

Internet

https://doi.org/10.1038/ncomms12521

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