Single-Chain Soluble Receptor Fusion Proteins as Versatile Cytokine Inhibitors

Cytokines are small secreted proteins that among many functions also play key roles in the orchestration of inflammation in host defense and disease. Over the past years, a large number of biologics have been developed to target cytokines in disease, amongst which soluble receptor fusion proteins ha...

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Bibliographic Details
Main Authors: Aurora Holgado, Harald Braun, Kenneth Verstraete, Domien Vanneste, Nico Callewaert, Savvas N. Savvides, Inna S. Afonina, Rudi Beyaert
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01422/full