The Synergic Role of Actomyosin Architecture and Biased Detachment in Muscle Energetics: Insights in Cross Bridge Mechanism beyond the Lever-Arm Swing

The Synergic Role of Actomyosin Architecture and Biased Detachment in Muscle Energetics: Insights in Cross Bridge Mechanism beyond the Lever-Arm Swing

Muscle energetics reflects the ability of myosin motors to convert chemical energy into mechanical energy. How this process takes place remains one of the most elusive questions in the field. Here, we combined experimental measurements of in vitro sliding velocity based on DNA-origami built filament...

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Bibliographic Details
Main Authors: Lorenzo Marcucci, Hiroki Fukunaga, Toshio Yanagida, Mitsuhiro Iwaki
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
Monte Carlo simulation
muscle energetics
Brownian ratchets
3D geometry
DNA origami
Online Access:https://www.mdpi.com/1422-0067/22/13/7037

Internet

https://www.mdpi.com/1422-0067/22/13/7037

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