IL-4Rα Polymorphism Is Associated With Myasthenia Gravis in Chinese Han Population

IL-4Rα Polymorphism Is Associated With Myasthenia Gravis in Chinese Han Population

Interleukin-4 (IL-4) is a potent growth and differentiation factor for B cells which play a vital role in the pathogenesis of myasthenia gravis (MG). IL-4 exerts its function by binding to three types of IL-4 receptor (IL-4R) complexes. IL-4Rα is the key component of the IL-4R complex. We hypothesiz...

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Bibliographic Details
Main Authors: Ping Jiang, Yao-Xian Yue, Yu Hong, Yanchen Xie, Xiang Gao, Chuan-Kai Gu, Hong-Jun Hao, Yue Qin, Xiao-Jun Ding, Min Song, Hai-Feng Li, Xu Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Neurology
Subjects:
myasthenia gravis
interleukin-4 receptor
polymorphism
susceptibility
severity
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.00529/full

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https://www.frontiersin.org/article/10.3389/fneur.2018.00529/full

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