Molecular mechanisms for synergistic effect of proteasome inhibitors with platinum-based therapy in solid tumors

The successful development of the proteasome inhibitor bortezomib as an anticancer drug has improved survival in patients with multiple myeloma. With the emergence of the newly US Food and Drug Administration-approved proteasome inhibitor carfilzomib, ongoing trials are investigating this compound a...

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Bibliographic Details
Main Authors: Angel Chao, Tzu-Hao Wang
Format: Article
Language:English
Published: Elsevier 2016-02-01
Series:Taiwanese Journal of Obstetrics & Gynecology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1028455915002879