Mir-338-3p Mediates Tnf-A-Induced Hepatic Insulin Resistance by Targeting PP4r1 to Regulate PP4 Expression

Mir-338-3p Mediates Tnf-A-Induced Hepatic Insulin Resistance by Targeting PP4r1 to Regulate PP4 Expression

Objective: Insulin resistance is a critical factor contributing to the pathogenesis of type 2 diabetes and other metabolic diseases. Recent studies have indicated that miR-338-3p plays an important role in cancer. Here, we investigated whether miR-338-3p mediates tumour necrosis factor-α (TNF-α)-ind...

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Bibliographic Details
Main Authors: Lin Dou, Shuyue Wang, Libo Sun, Xiuqing Huang, Yang Zhang, Tao Shen, Jun Guo, Yong Man, Weiqing Tang, Jian Li
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
miR-338-3p
Hepatic insulin resistance
PP4R1
TNF-α
Online Access:http://www.karger.com/Article/FullText/475912

Internet

http://www.karger.com/Article/FullText/475912

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