High-Sensitivity Fluorometry to Resolve Ion Channel Conformational Dynamics
Summary: Fluorescent labels offer the capability to follow conformational dynamics of membrane proteins, but signal detection in such recordings is inherently difficult to achieve in a cell membrane and lacks sufficient time resolution to follow physiologically relevant transitions. Here, we develop...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-02-01
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Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124718300615 |