Does External Exposure of Glycidol-Related Chemicals Influence the Forming of the Hemoglobin Adduct, <i>N</i>-(2,3-dihydroxypropyl)valine, as a Biomarker of Internal Exposure to Glycidol?

Glycidyl fatty acid esters (GE) are constituents of edible oils and fats, and are converted into glycidol, a genotoxic substance, in vivo. <i>N</i>-(2,3-dihydroxypropyl)valine (diHOPrVal), a hemoglobin adduct of glycidol, is used as a biomarker of glycidol and GE exposure. However, high...

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Bibliographic Details
Main Authors: Yuko Shimamura, Ryo Inagaki, Hiroshi Honda, Shuichi Masuda
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Toxics
Subjects:
Online Access:https://www.mdpi.com/2305-6304/8/4/119