A Single-Step Surface Modification of Electrospun Silica Nanofibers Using a Silica Binding Protein Fused with an RGD Motif for Enhanced PC12 Cell Growth and Differentiation

A Single-Step Surface Modification of Electrospun Silica Nanofibers Using a Silica Binding Protein Fused with an RGD Motif for Enhanced PC12 Cell Growth and Differentiation

In this study, a previously known high-affinity silica binding protein (SB) was genetically engineered to fuse with an integrin-binding peptide (RGD) to create a recombinant protein (SB-RGD). SB-RGD was successfully expressed in Escherichia coli and purified using silica beads through a simple and f...

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Bibliographic Details
Main Authors: Wen Shuo Chen, Ling Yu Guo, Amien Mohamed Masroujeh, Anna Morgan Augustine, Cheng Kang Tsai, Ting Yu Chin, Yui Whei Chen-Yang, Mong-Lin Yang
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Materials
Subjects:
electrospun silica nanofibers
silica binding protein
RGD
neuronal tissue engineering
Online Access:http://www.mdpi.com/1996-1944/11/6/927

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http://www.mdpi.com/1996-1944/11/6/927

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