Direct transfer of viral and cellular proteins from varicella-zoster virus-infected non-neuronal cells to human axons.

Varicella Zoster Virus (VZV), the alphaherpesvirus that causes varicella upon primary infection and Herpes zoster (shingles) following reactivation in latently infected neurons, is known to be fusogenic. It forms polynuclear syncytia in culture, in varicella skin lesions and in infected fetal human...

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Bibliographic Details
Main Authors: Sergei Grigoryan, Michael B Yee, Yair Glick, Doron Gerber, Eldad Kepten, Yuval Garini, In Hong Yang, Paul R Kinchington, Ronald S Goldstein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4431828?pdf=render