Expression of the Kynurenine Pathway in Human Peripheral Blood Mononuclear Cells: Implications for Inflammatory and Neurodegenerative Disease.

Expression of the Kynurenine Pathway in Human Peripheral Blood Mononuclear Cells: Implications for Inflammatory and Neurodegenerative Disease.

The kynurenine pathway is a fundamental mechanism of immunosuppression and peripheral tolerance. It is increasingly recognized as playing a major role in the pathogenesis of a wide variety of inflammatory, neurodegenerative and malignant disorders. However, the temporal dynamics of kynurenine pathwa...

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Bibliographic Details
Main Authors: Simon P Jones, Nunzio F Franco, Bianca Varney, Gayathri Sundaram, David A Brown, Josien de Bie, Chai K Lim, Gilles J Guillemin, Bruce J Brew
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4482723?pdf=render

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http://europepmc.org/articles/PMC4482723?pdf=render

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