Salidroside Protects Caenorhabditis elegans Neurons from Polyglutamine-Mediated Toxicity by Reducing Oxidative Stress

Salidroside Protects Caenorhabditis elegans Neurons from Polyglutamine-Mediated Toxicity by Reducing Oxidative Stress

Polyglutamine (polyQ) aggregation plays a pivotal role in the pathological process of Huntington’s disease and other polyQ disorders. Therefore, strategies aiming at restoring dysfunction and reducing stresses mediated by polyQ toxicity are of therapeutic interest for proteotoxicity diseases. Salid...

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Bibliographic Details
Main Authors: Lingyun Xiao, Haifeng Li, Ju Zhang, Fan Yang, Aizhen Huang, Jingjing Deng, Ming Liang, Fangli Ma, Minghua Hu, Zebo Huang
Format: Article
Language:English
Published: MDPI AG 2014-06-01
Series:Molecules
Subjects:
salidroside
polyglutamine
neurotoxicity
oxidative stress
C. elegans
chemoavoidance
Online Access:http://www.mdpi.com/1420-3049/19/6/7757

Internet

http://www.mdpi.com/1420-3049/19/6/7757

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