Cartilage-Specific Matrix and Integrin Expression in Three-Dimensional Articular Chondrocyte Cultures Overexpressing Human Interleukin-10

Interleukin (IL)-10 overexpression inhibits joint inflammation, however the effect of high local concentrations of IL-10 on chondrocyte homeostasis remains unclear. The aim of this study was to determine the effects of IL-10 overexpression on cartilage matrix production in three-dimensional (3D) cho...

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Bibliographic Details
Main Authors: Riccarda D. Müller, Thilo John, Benjamin Kohl, Anja Feldner, Hala Zreiqat, Wolfgang Ertel, Drake LaFace, Beth Hutchins, Andreas Oberholzer, Gundula Schulze-Tanzil M.D.
Format: Article
Language:English
Published: SAGE Publishing 2008-01-01
Series:Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders
Online Access:https://doi.org/10.4137/CMAMD.S560