Knockdown of THOC1 reduces the proliferation of hepatocellular carcinoma and increases the sensitivity to cisplatin

Knockdown of THOC1 reduces the proliferation of hepatocellular carcinoma and increases the sensitivity to cisplatin

Abstract Background Hepatocellular carcinoma (HCC) is one of the most common malignant cancers with poor prognosis and high incidence. The clinical data analysis of liver hepatocellular carcinoma samples downloaded from The Cancer Genome Atlas reveals that the THO Complex 1 (THOC1) is remarkable upr...

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Bibliographic Details
Main Authors: Shijiao Cai, Yunpeng Bai, Huan Wang, Zihan Zhao, Xiujuan Ding, Heng Zhang, Xiaoyun Zhang, Yantao Liu, Yan Jia, Yinan Li, Shuang Chen, Honggang Zhou, Huijuan Liu, Cheng Yang, Tao Sun
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
THOC1
R-loop
Proliferation
Luteolin
Cisplatin
Sensitivity
Online Access:http://link.springer.com/article/10.1186/s13046-020-01634-7

Internet

http://link.springer.com/article/10.1186/s13046-020-01634-7

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