Effect of ionization of drug on drug solubilization in SMEDDS prepared using Capmul MCM and caprylic acid

Effect of ionization of drug on drug solubilization in SMEDDS prepared using Capmul MCM and caprylic acid

The purpose of this study was to investigate the effect of ionization of drug on drug solubilization in SMEDDS (self-microemulsifying drug delivery system) prepared using Capmul MCM and caprylic acid. Solubilization capacity of blank SMEDDS dispersions for danazol, indomethacin and haloperidol as mo...

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Bibliographic Details
Main Authors: Suhua Li, Parshotam Madan, Senshang Lin
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
SMEDDS
Capmul MCM
Caprylic acid
Ionization
Indomethacin
Haloperidol
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087616301696

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http://www.sciencedirect.com/science/article/pii/S1818087616301696

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