Selected amino acid mutations in HIV-1 B subtype gp41 are Associated with Specific gp120<sub>V3 </sub>signatures in the regulation of Co-Receptor usage
<p>Abstract</p> <p>Background</p> <p>The third variable loop (V3) of the HIV-1 gp120 surface protein is a major determinant of cellular co-receptor binding. However, HIV-1 can also modulate its tropism through other regions in gp120, such as V1, V2 and C4 regions, as we...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2011-05-01
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| Series: | Retrovirology |
| Online Access: | http://www.retrovirology.com/content/8/1/33 |