At the Crossroads of Molecular Biology and Immunology: Molecular Pathways for Immunological Targeting of Head and Neck Squamous Cell Carcinoma

At the Crossroads of Molecular Biology and Immunology: Molecular Pathways for Immunological Targeting of Head and Neck Squamous Cell Carcinoma

Background: Recent advances in immunotherapy for head and neck squamous cell carcinoma (HNSCC) have led to implementation of anti-programmed death receptor 1 (PD-1) immunotherapy to standard of care for recurrent/metastatic HNSCC. However, the majority of tumors do not respond to these therapies, in...

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Bibliographic Details
Main Authors: Niels E. Wondergem, Dennis N. L. M. Nijenhuis, Jos B. Poell, C. René Leemans, Ruud H. Brakenhoff, Rieneke van de Ven
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oral Health
Subjects:
head and neck cancer
molecular targets
immune microenvironment
immunotherapy
signaling pathways
Online Access:https://www.frontiersin.org/articles/10.3389/froh.2021.647980/full

Internet

https://www.frontiersin.org/articles/10.3389/froh.2021.647980/full

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