Transcriptionally active enhancers in human cancer cells

Abstract The growth of human cancer cells is driven by aberrant enhancer and gene transcription activity. Here, we use transient transcriptome sequencing (TT‐seq) to map thousands of transcriptionally active putative enhancers in fourteen human cancer cell lines covering seven types of cancer. These...

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Bibliographic Details
Main Authors: Katja Lidschreiber, Lisa A Jung, Henrik von derEmde, Kashyap Dave, Jussi Taipale, Patrick Cramer, Michael Lidschreiber
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.15252/msb.20209873