Optimization of scleroglucan production by Sclerotium rolfsii by lowering pH during fermentation via oxalate metabolic pathway manipulation using CRISPR/Cas9

Optimization of scleroglucan production by Sclerotium rolfsii by lowering pH during fermentation via oxalate metabolic pathway manipulation using CRISPR/Cas9

Abstract Background Sclerotium rolfsii is a potent producer of many secondary metabolites, one of which like scleroglucan is an exopolysaccharide (EPS) appreciated as a multipurpose compound applicable in many industrial fields. Results Aspartate transaminase (AAT1) catalyzes the interconversion of...

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Bibliographic Details
Main Authors: Tianlong Bai, Teng Wang, Yan Li, Na L. Gao, Lixin Zhang, Wei-Hua Chen, Xiushan Yin
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Fungal Biology and Biotechnology
Subjects:
AAT1
CRISPR/Cas9
Oxalate
Scleroglucan
Sclerotium rolfsii
Online Access:https://doi.org/10.1186/s40694-021-00108-5

Internet

https://doi.org/10.1186/s40694-021-00108-5

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