The potential role of metformin in the treatment of patients with pancreatic neuroendocrine tumors: a review of preclinical to clinical evidence

The incidence of pancreatic neuroendocrine tumors (panNETs) has increased worldwide in the last two decades. Given the indolent nature of these tumors, several patients are diagnosed with metastatic disease, which partially impairs the long-term efficacy of currently available treatments and reduces...

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Main Authors: Sara Pusceddu, Claudio Vernieri, Natalie Prinzi, Martina Torchio, Jorgelina Coppa, Maria Antista, Monica Niger, Massimo Milione, Luca Giacomelli, Francesca Corti, Michele Prisciandaro, Michela Monteleone, Elena Colombo, Maria Di Bartolomeo, Filppo de Braud
Format: Article
Language:English
Published: SAGE Publishing 2020-07-01
Series:Therapeutic Advances in Gastroenterology
Online Access:https://doi.org/10.1177/1756284820927271