Peptide P5 (residues 628–683), comprising the entire membrane proximal region of HIV-1 gp41 and its calcium-binding site, is a potent inhibitor of HIV-1 infection
<p>Abstract</p> <p>The membrane proximal region (MPR) of the transmembrane subunit, gp41, of the HIV envelope glycoprotein plays a critical role in HIV-1 infection of CD4<sup>+</sup> target cells and CD4-independent mucosal entry. It contains continuous epitopes recogni...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2008-10-01
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| Series: | Retrovirology |
| Online Access: | http://www.retrovirology.com/content/5/1/93 |