DNA damage and synaptic and behavioural disorders in glucose-6-phosphate dehydrogenase-deficient mice

DNA damage and synaptic and behavioural disorders in glucose-6-phosphate dehydrogenase-deficient mice

Mice deficient in glucose-6-phosphate dehydrogenase (G6PD) cannot replenish the cellular antioxidant glutathione, which detoxifies neurodegenerative reactive oxygen species (ROS). To determine the functional consequences of G6PD deficiency, young and aging G6PD-deficient mice were evaluated for brai...

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Bibliographic Details
Main Authors: Margaret M. Loniewska, Anmol Gupta, Shama Bhatia, Isabel MacKay-Clackett, Zhengping Jia, Peter G. Wells
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231719308146

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http://www.sciencedirect.com/science/article/pii/S2213231719308146

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