Hypoxia and transforming growth factor β1 regulation of long non‐coding RNA transcriptomes in human pulmonary fibroblasts

Abstract One of the key characteristics of idiopathic pulmonary fibrosis (IPF) is accumulation of excess fibrous tissue in the lung, which leads to hypoxic conditions. Transforming growth factor (TGF) β is a major mediator that promotes the differentiation of fibroblasts to myofibroblasts. However,...

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Bibliographic Details
Main Authors: Lakmini K. Senavirathna, Chaoqun Huang, Samuel Pushparaj, Dao Xu, Lin Liu
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.14343