Identification of Egr1 as the oncostatin M-induced transcription activator that binds to sterol-independent regulatory element of human LDL receptor promoter

Identification of Egr1 as the oncostatin M-induced transcription activator that binds to sterol-independent regulatory element of human LDL receptor promoter

Previously, we identified the low density lipoprotein receptor (LDLR) promoter region −17 to −1 as a novel sterol-independent regulatory element (SIRE) that mediates the stimulating effect of oncostatin M (OM). The goal of this study was to identify the OM-induced transcription activator that binds...

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Bibliographic Details
Main Authors: Fang Zhang, Thomas E. Ahlborn, Cong Li, Fredric B. Kraemer, Jingwen Liu
Format: Article
Language:English
Published: Elsevier 2002-09-01
Series:Journal of Lipid Research
Subjects:
cytokines
early growth response gene 1
gene transcription
transcriptional activation
signal transduction
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520328121

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http://www.sciencedirect.com/science/article/pii/S0022227520328121

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