UCP1 deficiency increases adipose tissue monounsaturated fatty acid synthesis and trafficking to the liver

Uncoupling protein-1 (UCP1) facilitates thermogenesis in brown and beige adipocytes and can promote energy expenditure by decreasing mitochondrial respiratory efficiency. Defects in UCP1 and brown adipose tissue thermogenesis subject animals to chronic cold stress and elicit compensatory responses t...

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Bibliographic Details
Main Authors: Laura M. Bond, James M. Ntambi
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520342279