Myeloid cell deletion of Aryl hydrocarbon Receptor Nuclear Translocator (ARNT) induces non-alcoholic steatohepatitis.

Myeloid cell deletion of Aryl hydrocarbon Receptor Nuclear Translocator (ARNT) induces non-alcoholic steatohepatitis.

BACKGROUND AND AIM:Non-alcoholic steatohepatitis (NASH) is predicted to become the most common cause of cirrhosis and liver failure. Risk factors include obesity, insulin resistance and diabetes. Macrophages and other myeloid cells play crucial roles in initiating and driving inflammation. Aryl hydr...

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Bibliographic Details
Main Authors: Christopher Scott, Rebecca Stokes, Kuan Minn Cha, Andrew Clouston, Mohammed Eslam, Mayda Metwally, Michael M Swarbrick, Jacob George, Jenny E Gunton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0225332

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https://doi.org/10.1371/journal.pone.0225332

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