Antiviral Drug–Resistant Influenza B Viruses Carrying H134N Substitution in Neuraminidase, Laos, February 2016

Antiviral Drug–Resistant Influenza B Viruses Carrying H134N Substitution in Neuraminidase, Laos, February 2016

In February 2016, three influenza B/Victoria/2/87 lineage viruses exhibiting 4- to 158-fold reduced inhibition by neuraminidase inhibitors were detected in Laos. These viruses had an H134N substitution in the neuraminidase and replicated efficiently in vitro and in ferrets. Current antiviral drugs m...

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Bibliographic Details
Main Authors: Tatiana Baranovich, Phengta Vongphrachanh, Pakapak Ketmayoon, Thongchanh Sisouk, Khampheng Chomlasack, Viengphone Khanthamaly, Ha Thuy Nguyen, Vasiliy P. Mishin, Henju Marjuki, John Barnes, Rebecca J. Garten, James Stevens, David Wentworth, Larisa Gubareva
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2017-04-01
Series:Emerging Infectious Diseases
Subjects:
influenza B viruses
H134N substitution
mutation
neuraminidase
viruses
antiviral drug–resistant
Online Access:https://wwwnc.cdc.gov/eid/article/23/4/16-1876_article

Internet

https://wwwnc.cdc.gov/eid/article/23/4/16-1876_article

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