Flavonoids as Potential Drugs for <i>VPS13</i>-Dependent Rare Neurodegenerative Diseases

Flavonoids as Potential Drugs for <i>VPS13</i>-Dependent Rare Neurodegenerative Diseases

Several rare neurodegenerative diseases, including chorea acanthocytosis, are caused by mutations in the <i>VPS13A</i>–<i>D</i> genes. Only symptomatic treatments for these diseases are available. <i>Saccharomyces cerevisiae</i> contains a unique <i>VPS13<...

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Bibliographic Details
Main Authors: Piotr Soczewka, Krzysztof Flis, Déborah Tribouillard-Tanvier, Jean-Paul di Rago, Cláudia N. Santos, Regina Menezes, Joanna Kaminska, Teresa Zoladek
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Genes
Subjects:
yeast model
neurodegenerative diseases
<i>VPS13</i> genes
drug repurposing
luteolin
tolcapone
Online Access:https://www.mdpi.com/2073-4425/11/7/828

Internet

https://www.mdpi.com/2073-4425/11/7/828

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