Up-regulation and profibrotic role of osteopontin in human idiopathic pulmonary fibrosis.

Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal disorder characterized by fibroproliferation and excessive accumulation of extracellular matrix in the lung.Using oligonucleotide arrays, we identified osteopontin as one of the genes that significantly distinguishes IPF from normal lun...

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Bibliographic Details
Main Authors: Annie Pardo, Kevin Gibson, José Cisneros, Thomas J Richards, Yinke Yang, Carina Becerril, Samueal Yousem, Iliana Herrera, Victor Ruiz, Moisés Selman, Naftali Kaminski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-09-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC1198037?pdf=render