Improving NKCC1 Function Increases the Excitability of DRG Neurons Exacerbating Pain Induced After TRPV1 Activation of Primary Sensory Neurons

Improving NKCC1 Function Increases the Excitability of DRG Neurons Exacerbating Pain Induced After TRPV1 Activation of Primary Sensory Neurons

Background Our aim was to investigate the effects of the protein expression and the function of sodium, potassium, and chloride co-transporter (NKCC1) in the dorsal root ganglion (DRG) after activation of transient receptor potential vanilloid 1 receptor (TRPV1) in capsaicin-induced acute inflammato...

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Bibliographic Details
Main Authors: Shi-Yu Deng, Xue-Chun Tang, Yue-Chen Chang, Zhen-Zhen Xu, Qin-Yi Chen, Nan Cao, Liang-Jing-Yuan Kong, Yang Wang, Ke-Tao Ma, Li Li, Jun-Qiang Si
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
DRG
NKCC1
TRPV1
capsaicin
pain
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.665596/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2021.665596/full

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