Differentiation in the protein synthesis-dependency of persistent synaptic plasticity in mossy fiber and associational/commissural CA3 synapses in vivo

Long-term potentiation (LTP) and long-term depression (LTD) are two mechanisms involved in the long-term storage of information in hippocampal synapses. In the hippocampal CA1 region, the late phases of LTP and LTD are protein-synthesis dependent. In the dentate gyrus, late-LTP but not LTD requires...

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Bibliographic Details
Main Authors: Hardy eHagena, Denise eManahan-Vaughan
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-03-01
Series:Frontiers in Integrative Neuroscience
Subjects:
CA3
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnint.2013.00010/full