Signalling crosstalk in FGF2-mediated protection of endothelial cells from HIV-gp120

<p>Abstract</p> <p>Background</p> <p>The blood brain barrier (BBB) is the first line of defence of the central nervous system (CNS) against circulating pathogens, such as HIV. The cytotoxic HIV protein, gp120, damages endothelial cells of the BBB, thereby compromising i...

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Bibliographic Details
Main Authors: Digicaylioglu Murat, Hashimoto Makoto, Hurford Rosemary, Langford Dianne, Masliah Eliezer
Format: Article
Language:English
Published: BMC 2005-02-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/6/8