Enhanced translation expands the endo-lysosome size and promotes antigen presentation during phagocyte activation.
The mechanisms that govern organelle adaptation and remodelling remain poorly defined. The endo-lysosomal system degrades cargo from various routes, including endocytosis, phagocytosis, and autophagy. For phagocytes, endosomes and lysosomes (endo-lysosomes) are kingpin organelles because they are es...
Main Authors: | Victoria E B Hipolito, Jacqueline A Diaz, Kristofferson V Tandoc, Christian Oertlin, Johannes Ristau, Neha Chauhan, Amra Saric, Shannon Mclaughlan, Ola Larsson, Ivan Topisirovic, Roberto J Botelho |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-12-01
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Series: | PLoS Biology |
Online Access: | https://doi.org/10.1371/journal.pbio.3000535 |
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