Selective inhibition of JAK3 signaling is sufficient to reverse alopecia areata

The Janus kinase/signal transducers and activators of transcription (JAK/STAT) are key intracellular mediators in the signal transduction of many cytokines and growth factors. Common γ chain cytokines and interferon-γ that use the JAK/STAT pathway to induce biological responses have been implicated...

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Bibliographic Details
Main Authors: Zhenpeng Dai, James Chen, Yuqian Chang, Angela M. Christiano
Format: Article
Language:English
Published: American Society for Clinical investigation 2021-04-01
Series:JCI Insight
Subjects:
Online Access:https://doi.org/10.1172/jci.insight.142205