Modulatory effects of inhibition on persistent activity in a cortical microcircuit model

Modulatory effects of inhibition on persistent activity in a cortical microcircuit model

Neocortical network activity is generated through a dynamic balance between excitation, provided by pyramidal neurons, and inhibition, provided by interneurons. Imbalance of the excitation/inhibition ratio has been identified in several neuropsychiatric diseases, such as schizophrenia, autism and e...

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Bibliographic Details
Main Authors: XANTHIPPI eKONSTANTOUDAKI, Athanasia ePapoutsi, Kleanthi eChalkiadaki, Panayiota ePoirazi, Kyriaki eSidiropoulou
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-01-01
Series:Frontiers in Neural Circuits
Subjects:
Prefrontal Cortex
connectivity
NMDA
fast-spiking interneurons
parvalbumin interneurons
synchronicity
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncir.2014.00007/full

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http://journal.frontiersin.org/Journal/10.3389/fncir.2014.00007/full

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