1-O-Sulfatobastadins-1 and -2 from Ianthella basta (Pallas).Antagonists of the yR1-FKBP12 Ca2+ Channel

Abstract: Two new sulfate monoesters of hemibastadins-1 and -2 were isolated from the marine sponge Ianthella basta (Pallas) from Guam. A third new compound was tentatively assigned the structure 34-O-sulfatobastadin-9. The 1-O-sulfatohemibastadins-1 and –2 were antagonists of the RyR1-FKBP12 C...

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Bibliographic Details
Main Authors: Tadeusz F. Molinski, Isaac N. Pessah, Alexander C. Hoepker, Makoto N. Masuno
Format: Article
Language:English
Published: MDPI AG 2004-11-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/2/4/176/