Identification of Niemann-Pick C1 disease biomarkers through sphingolipid profiling

Identification of Niemann-Pick C1 disease biomarkers through sphingolipid profiling

Niemann-Pick type C (NPC)1 is a rare neurodegenerative disease for which treatment options are limited. A major barrier to development of effective treatments has been the lack of validated biomarkers to monitor disease progression or serve as outcome measures in clinical trials. Using targeted meta...

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Bibliographic Details
Main Authors: Martin Fan, Rohini Sidhu, Hideji Fujiwara, Brett Tortelli, Jessie Zhang, Cristin Davidson, Steven U. Walkley, Jessica H. Bagel, Charles Vite, Nicole M. Yanjanin, Forbes D. Porter, Jean E. Schaffer, Daniel S. Ory
Format: Article
Language:English
Published: Elsevier 2013-10-01
Series:Journal of Lipid Research
Subjects:
metabolomics
neurodegeneration
sphingolipids
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520353062

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http://www.sciencedirect.com/science/article/pii/S0022227520353062

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