Transcriptional activation of muscle atrophy promotes cardiac muscle remodeling during mammalian hibernation
Background. Mammalian hibernation in thirteen-lined ground squirrels (Ictidomys tridecemlineatus) is characterized by dramatic changes on a physiological and molecular level. During hibernation, mammalian hearts show a propensity to hypertrophy due to the need for increasing contractility to pump co...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2016-08-01
|
Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/2317.pdf |