IL-1β promotes corneal epithelial cell migration by increasing MMP-9 expression through NF-κB- and AP-1-dependent pathways.

Interleukin-1β (IL-1β) plays a critical mediator in the pathogenesis of eye diseases. The implication of IL-1β in inflammatory responses has been shown to be mediated through up-regulation of inflammatory genes, including matrix metalloproteinase-9 (MMP-9). However, the detailed mechanisms of IL-1β-...

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Bibliographic Details
Main Authors:	Hui-Ching Tseng, I-Ta Lee, Chih-Chung Lin, Pei-Ling Chi, Shin-Ei Cheng, Ruey-Horng Shih, Li-Der Hsiao, Chuen-Mao Yang
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2013-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3591450?pdf=render

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http://europepmc.org/articles/PMC3591450?pdf=render

IL-1β promotes corneal epithelial cell migration by increasing MMP-9 expression through NF-κB- and AP-1-dependent pathways.

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