Mutations in <it>LRP5 </it>cause primary osteoporosis without features of OI by reducing Wnt signaling activity
<p>Abstract</p> <p>Background</p> <p>Primary osteoporosis is a rare childhood-onset skeletal condition whose pathogenesis has been largely unknown. We have previously shown that primary osteoporosis can be caused by heterozygous missense mutations in the Low-density lip...
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2012-04-01
|
| Series: | BMC Medical Genetics |
| Online Access: | http://www.biomedcentral.com/1471-2350/13/26 |