Co-inherited mutations of Fas and caspase-10 in development of the autoimmune lymphoproliferative syndrome

<p>Abstract</p> <p>Background</p> <p>Autoimmune lymphoproliferative syndrome (ALPS) is a rare inherited disorder characterized by defective function of Fas, autoimmune manifestations that predominantly involve blood cells, polyclonal accumulation of lymphocytes in the s...

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Main Authors: Lenardo Michael J, Chiocchetti Annalisa, Rosolen Angelo, Crescenzio Nicoletta, Garelli Emanuela, Ferretti Massimo, Campagnoli Maria F, Cerutti Elisa, Ramenghi Ugo, Dianzani Umberto
Format: Article
Language:English
Published: BMC 2007-11-01
Series:BMC Immunology
Online Access:http://www.biomedcentral.com/1471-2172/8/28