Insulin Receptor Substrate 2 Controls Insulin-Mediated Vasoreactivity and Perivascular Adipose Tissue Function in Muscle

Insulin Receptor Substrate 2 Controls Insulin-Mediated Vasoreactivity and Perivascular Adipose Tissue Function in Muscle

Introduction: Insulin signaling in adipose tissue has been shown to regulate insulin's effects in muscle. In muscle, perivascular adipose tissue (PVAT) and vascular insulin signaling regulate muscle perfusion. Insulin receptor substrate (IRS) 2 has been shown to control adipose tissue function...

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Bibliographic Details
Main Authors: Alexander H. Turaihi, Wineke Bakker, Victor W. M. van Hinsbergh, Erik H. Serné, Yvo M. Smulders, Hans W. M. Niessen, Etto C. Eringa
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Physiology
Subjects:
insulin sensitivity
perivascular adipose tissue
insulin receptor substrate 2
microcirculation
endothelium
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2018.00245/full

Internet

http://journal.frontiersin.org/article/10.3389/fphys.2018.00245/full

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