Salvianolic Acid B Promotes the Survival of Random-Pattern Skin Flaps in Rats by Inducing Autophagy

Salvianolic Acid B Promotes the Survival of Random-Pattern Skin Flaps in Rats by Inducing Autophagy

Random-pattern skin flap transplantation is frequently applied in plastic and reconstructive surgery. However, the distal part of the flap often suffers necrosis due to ischemia. In this study, the effects of salvianolic acid B (Sal B) on flap survival were evaluated, and the underlying mechanisms w...

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Bibliographic Details
Main Authors: Jinti Lin, Renjin Lin, Shihen Li, Hongqiang Wu, Jian Ding, Guangheng Xiang, Shi Li, Yiru Wang, Dingsheng Lin, Weiyang Gao, Jianzhong Kong, Huazi Xu, Kailiang Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Pharmacology
Subjects:
salvianolic acid B
random skin flap
autophagy
angiogenesis
apoptosis
oxidative stress
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01178/full

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https://www.frontiersin.org/article/10.3389/fphar.2018.01178/full

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