Targeting Endoplasmic Reticulum and/or Mitochondrial Ca2+ Fluxes as Therapeutic Strategy for HCV Infection

Chronic hepatitis C is characterized by metabolic disorders and by a microenvironment in the liver dominated by oxidative stress, inflammation and regeneration processes that can in the long term lead to liver cirrhosis and hepatocellular carcinoma. Several lines of evidence suggest that mitochondri...

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Bibliographic Details
Main Authors: Rosella Scrima, Claudia Piccoli, Darius Moradpour, Nazzareno Capitanio
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Chemistry
Subjects:
HCV
Online Access:http://journal.frontiersin.org/article/10.3389/fchem.2018.00073/full