Targeting Endoplasmic Reticulum and/or Mitochondrial Ca2+ Fluxes as Therapeutic Strategy for HCV Infection
Chronic hepatitis C is characterized by metabolic disorders and by a microenvironment in the liver dominated by oxidative stress, inflammation and regeneration processes that can in the long term lead to liver cirrhosis and hepatocellular carcinoma. Several lines of evidence suggest that mitochondri...
Main Authors: | Rosella Scrima, Claudia Piccoli, Darius Moradpour, Nazzareno Capitanio |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2018-03-01
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Series: | Frontiers in Chemistry |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fchem.2018.00073/full |
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