Gut microbiota mediated the therapeutic efficacies and the side effects of prednisone in the treatment of MRL/lpr mice

Gut microbiota mediated the therapeutic efficacies and the side effects of prednisone in the treatment of MRL/lpr mice

Abstract Background Growing evidences indicate that the alterations in gut microbiota are associated with the efficacy of glucocorticoids (GCs) in the treatment of systemic lupus erythematosus (SLE). However, there is no evidence to prove whether gut microbiota directly mediates the effects of GCs....

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Bibliographic Details
Main Authors: Mingzhu Wang, Zhengyang Zhu, Xiaoying Lin, Haichang Li, Chengping Wen, Jie Bao, Zhixing He
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Arthritis Research & Therapy
Subjects:
Systemic lupus erythematosus
Gut microbiota
Prednisone
Fecal microbiota transplantation
MRL/lpr mice
Online Access:https://doi.org/10.1186/s13075-021-02620-w

Internet

https://doi.org/10.1186/s13075-021-02620-w

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