p21<sup>WAF1 </sup>expression induced by MEK/ERK pathway activation or inhibition correlates with growth arrest, myogenic differentiation and onco-phenotype reversal in rhabdomyosarcoma cells
<p>Abstract</p> <p>Background</p> <p>p21<sup>WAF1</sup>, implicated in the cell cycle control of both normal and malignant cells, can be induced by p53-dependent and independent mechanisms. In some cells, MEKs/ERKs regulate p21<sup>WAF1 </sup>tra...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2005-12-01
|
| Series: | Molecular Cancer |
| Online Access: | http://www.molecular-cancer.com/content/4/1/41 |